Purified Anti-Human CD101 Antibody[BB27] (E-AB-F1361A)
![Purified Anti-Human CD101 Antibody[BB27] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Unconjugated
APC Elab Fluor®700 PE PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
| Alternate Names | EWI, IGSF, P126, EWI101, IGSF2, V7, CD101, p126, IGSF2 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood granulocytes cell |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member of EWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higher inhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production. |
| Immunogen | Recombinant Human CD101 protein |
| Abbre | CD101 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology;CDs |
| Cellular Localization |
Membrane
|
| Tissue Specificity |
Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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